Despite the success of direct-acting antiviral (DAA) agents in treating chronic hepatitis C virus (HCV) infection, the number of cases of HCV-related hepatocellular carcinoma (HCC) is expected to increase over the next five years.HCC develops over the span of decades and is closely associated with fibrosis stage.HCV both directly and indirectly est
Bioregulatory event extraction using large language models: a case study of rice literature
Abstract The extraction of biological regulation events has been Motors a key focus in the field of biomedical nature language processing (BioNLP).However, existing methods often encounter challenges such as cascading errors in text mining pipelines and limitations in topic coverage from the selected corpus.Fortunately, the emergence of large langu
Design of plasma shutters for improved heavy ion acceleration by ultra-intense laser pulses
In this work, we investigate the application of the plasma shutters for heavy ion acceleration RAIN ORAL SPRAY driven by a high-intensity laser pulse.We use particle-in-cell and hydrodynamic simulations.The laser pulse, transmitted through the opaque shutter, gains a steep-rising front and its peak intensity is locally increased at the cost of losi
A West Mediterranean Story. The Struggle for power in Carthage during the second Half of the Third Century BC
The interest of classical literature on the Phone Socket conflict that confronted Rome against Carthage allows us to study aspects of the history of this ancient Tyrian colony that are virtually unknown to other historical periods.Despite the prominence of the Barcid family and his closest associates in the historical events of this period, the sup